RESTORE

RESTORE is a probiotic solution formulated to restore gut health while and after taking antibiotics. Developed by AMILI, a Singapore-based gut microbiome company, RESTORE is designed to reduce damage to the gut flora and RESTORE functional microbial diversity during and after a course of antibiotics.

What are antibiotics?

The discovery of antibiotics in 1928 has saved and transformed millions of lives. Mainly prescribed for treating infections (not viruses), antibiotics kill or slow down the growth of disease-causing bacteria. And while they do a good job in treating bacterial infections, antibiotics cannot differentiate between good and bad bacteria in the gut. They also kill the good bacteria, which may cause damage to the gut flora.

How does the misuse/prolonged use of antibiotics affect the gut microbiome?

As previously mentioned, antibiotics also eliminate friendly bacteria that keep the gut healthy. The overuse or misuse of antibiotics can significantly change the amount and type of bacteria in the gut. This can also lead to the growth of antibiotic-resistant bacteria and infections, resulting in bacterial resistance or antibiotic resistance. Prolonged antibiotic use:

  • Can cause an upset stomach or diarrhea due to the disruption in the gut ecosystem
  • Can lead to an imbalance in the microbiome (which may result in gastrointestinal symptoms)
  • Decreases the diversity of microbes in the gut
  • Can cause lasting changes in the gut flora

How RESTORE benefits gut health

Probiotics are live bacteria and yeast that help promote a healthy digestion and balance of gut bacteria[1]. Studies suggest that they help reduce the side effects of antibiotics, such as antibiotic-associated diarrhea [2]. They replenish friendly bacteria in the gut, which then prevents disruption in the gut’s microbiome balance. 

Using the company’s own Asian microbiome database and public domain literature, the scientists at AMILI studied the effects of the most commonly prescribed antibiotics. This led to the development of RESTORE, a scientifically formulated probiotic solution for restoring gut health during and after completion of a course of antibiotics. It can reduce:

  • Antibiotics-related diarrhea
  • Bloating
  • Abdominal pain
  • Indigestion

Key benefits of RESTORE:

    • Contains beneficial probiotics to restore gut microbiome
    • Contains prebiotics to induce growth of beneficial bacteria
    • Contains postbiotics to further provide physiological benefits for wellbeing
    • Delayed-release capsules to deliver the beneficial active ingredients further into the gastrointestinal tract

How does RESTORE work?

A course of antibiotic treatment can disrupt your gut microbiome, harming the healthy gut bacteria and causing an imbalance that may persist long after the antibiotics have done their job. RESTORE probiotic solution can help counteract these effects by: 

  • Replenishing beneficial bacteria – or increasing the levels of friendly bacteria that were targeted or depleted during and after a course of antibiotics.  This helps promote a healthy and balanced gut microbiome.
  • Eliminating harmful pathogens – or controlling harmful bacteria that can contribute to the development of post-antibiotic symptoms and infections.
  • Improving gut health and function – by enhancing microbial diversity that supports better digestion, nutrient absorption, and overall gut health.

According to clinical study, RESTORE has a positive impact on the gut microbiome after a period of 14 days. Key points in the findings include:

  • RESTORE capsules were safe for consumption and benefitted both the gut microbiome and overall health of those who had been on a course of antibiotics.
  • RESTORE raised the levels of health-promoting bacterial species.
  • RESTORE resulted in the elimination of seven opportunistic pathogens that caused various infections and post-antibiotic symptoms.

How to use RESTORE

To be taken during and after completion of a course of antibiotics. 

Discontinue the course of probiotics before the end of two weeks to ensure sustained probiotic engraftment and the best health outcomes.

References:

  1. Maftei, N.-M.; Raileanu, C.R.; Balta, A.A.; Ambrose, L.; Boev, M.; Marin, D.B.; Lisa, E.L. The Potential Impact of Probiotics on Human Health: An Update on Their Health-Promoting Properties. Microorganisms 2024, 12, 234. https://doi.org/10.3390/microorganisms12020234
  2. Kopacz, K., & Phadtare, S. (2022). Probiotics for the Prevention of Antibiotic-Associated Diarrhea. Healthcare (Basel, Switzerland), 10(8), 1450. https://doi.org/10.3390/healthcare10081450